Proline is an amino acid, or a building block for protein. The body can make proline on its own, but it is also consumed in the diet. A typical diet contains about 5 grams of proline daily. The primary sources are protein-rich foods including meat, fish, and dairy. Proline can also be taken as a supplement.
Proline is used for skin healing, especially in people who have problems keeping enough proline in the body. It is also used for other conditions, but there is no good scientific evidence to support any of these uses.
In medicine, proline is used as a stabilizer to help some prescription products last longer.
Is It Effective?
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
- Athletic performance. Teens who eat more proline in the diet don't seem to be any more physically fit than teens who eat less proline.
- Low bone mass (osteopenia). Eating more proline in the diet doesn't seem to protect against osteopenia.
- Weak and brittle bones (osteoporosis). Eating more proline in the diet doesn't seem to protect against osteoporosis.
- Fractures.
- Fatigue.
- Insomnia.
- Infections.
- Wrinkles.
- Wound healing.
- Skin ulcers.
- Defects in proline metabolism.
More evidence is needed to rate the effectiveness of proline for these uses.
Is it Safe?
The body uses proline to make proteins, such as collagen. Collagen is found in the skin, bones, and joints. Proline is also involved in the general function of cells.
When taken by mouth: Proline is LIKELY SAFE when taken by mouth in food amounts. There isn't enough reliable information to know if proline is safe when used in larger amounts as medicine or what the side effects might be.
When applied to the skin: There isn't enough reliable information to know if proline is safe or what the side effects might be.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if proline is safe to use when pregnant or breast-feeding. Stay on the safe side and stick to the amounts found in foods.
Children: Proline is LIKELY SAFE when taken by mouth in food amounts.
It is not known if Proline interacts with any medicines. Before taking Proline, talk with your healthcare professional if you take any medications.
There are no known interactions with herbs and supplements.
There are no known interactions with foods.
The appropriate dose of proline depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for proline. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Hydroxyproline, L-hydroxyproline, L-Proline, Proline Rich Peptides, Proline-Rich Polypeptides, PRPs, Pyrrolidine-2-carboxylic acid.
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