Health & Well-Being A-Z

Ciguatoxins

different fish that produce Ciguatoxins
Description

Ciguatoxins are a group of poison that can accumulate in certain fish. Ciguatoxins are not used as a medicine.

Ciguatoxins cause a type of food poisoning called ciguatera. People can get ciguatera by eating normally safe, bottom-feeding, coral reef fish that have collected the poison from the food chain. This poisoning tends to occur near areas of disturbed reef, including severe weather and waterfront construction. Many different types of fish can be contaminated. The most common are large predatory reef fish, such as moray eels, snappers, groupers, barracuda, jacks, surgeons, Spanish mackerel, and humphead wrasse. There are no good “rules of thumb” for detecting tainted fish. They look, taste, and smell normal. The best way to avoid eating contaminated fish is to avoid eating the organs or head of large fish that came from an area around a reef.

Is It Effective?

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Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

Insufficient evidence
  • Ciguatoxins do not have any medicinal uses.

Is it Safe?

Action

Ciguatoxins interferes with the normal function of nerve cells.

Safety

Ciguatoxins are UNSAFE when taken by mouth. One bite of fish tainted with ciguatoxins can be enough to cause symptoms. The most common symptoms include stomach cramps, nausea, vomiting, and diarrhea. Other symptoms include itching; numbness of lips, tongue, and throat; blurred vision; low blood pressure; slowed heart rate; alternating hot and cold sensations; and coma. In severe cases, shock, muscular paralysis, and death can occur.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Ciguatoxins are UNSAFE for anyone, including pregnant and breast-feeding women. One pregnant woman who was poisoned suffered a miscarriage. Breast-feeding women should be especially careful to avoid ciguatoxins because they pass into breast milk and can affect the nursing infant.

Drug interactions

It is not known if Ciguatoxins interacts with any medicines. Before taking Ciguatoxins, talk with your healthcare professional if you take any medications.

Herb interactions

There are no known interactions with herbs and supplements.

Food interactions

Alcohol: Ciguatoxins can cause a type of food poisoning called ciguatera. Symptoms of ciguatera sometimes return in recently affected people after they have had alcohol. Some doctors recommend that patients avoid alcohol for several months after being diagnosed with ciguatera.


Caffeine-containing foods and drinks (coffee, tea, chocolate): Ciguatoxins can cause a type of food poisoning called ciguatera. Symptoms of ciguatera sometimes return in recently affected people after they have had caffeine. Some doctors recommend that patients avoid coffee, tea, and chocolate for several months after being diagnosed with ciguatera.


Fish: Ciguatoxins can cause a type of food poisoning called ciguatera. Symptoms of ciguatera sometimes return in recently affected people after they have had other types of fish, even if does not contain the toxin. Some doctors recommend that patients avoid fish for several months after being diagnosed with ciguatera.


Meat: Ciguatoxins can cause a type of food poisoning called ciguatera. Symptoms of ciguatera sometimes return in recently affected people after they have had meat, especially chicken and pork.


Nuts: Ciguatoxins can cause a type of food poisoning called ciguatera. Symptoms of ciguatera sometimes return in recently affected people after they have had nuts. Some doctors recommend that patients avoid nuts for several months after being diagnosed with ciguatera.

Dosage

The appropriate dose of ciguatoxins depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for ciguatoxins. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Other names

C-CTX, C-CTX-1, C-CTX-2, Ciguatera Toxins, Ciguatoxin 1, Ciguatoxin-1B, Ciguatoxin 2, Ciguatoxin 3, Ciguatoxin 4B, CTX, CTX-1, CTX-2, CTX-3, CTX-4, CTX1B, CTX2A1, CTX2A2, CTX2B2, CTX3C, CTX4A, CTX4B, Gambiertoxin, GTX-4B, Gt 4b, I-CTX, P-CTX, P-CTX-1, P-CTX-1B, P-CTX-2, P-CTX-3, Pacific Ciguatoxin 1, Pacific ciguatoxin-3C, 2,3-dihydroxyCTX3C, 52-epi-54-deoxyCTX, 54-deoxyCTX.

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