Gamma-oryzanol is group of chemicals found in rice bran oil. It is also found in wheat bran and some fruits and vegetables.
Gamma-oryzanol isn't absorbed well in the gut. Because of this, it might reduce cholesterol levels by reducing how much cholesterol is absorbed from foods.
People use gamma-oryzanol for high cholesterol, symptoms of menopause, athletic performance, eczema, high blood pressure, and many other conditions, but there is no good scientific evidence to support most of these uses.
Is It Effective?
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
- Abnormal levels of cholesterol or blood fats (dyslipidemia). Taking gamma-oryzanol by mouth might decrease total cholesterol, low-density lipoprotein (LDL or "bad") cholesterol, and blood fats called triglycerides in people with high cholesterol.
There is interest in using gamma-oryzanol for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
Is it Safe?
When taken by mouth: Gamma-oryzanol is possibly safe when used in doses up to 300 mg daily. It seems to be well-tolerated.
When applied to the skin: Gamma-oryzanol is possibly safe when used appropriately.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if gamma-oryzanol is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Thyroid conditions: Gamma-oryzanol might change thyroid function. Speak with a healthcare provider before using gamma-oryzanol if you have a thyroid condition.
It is not known if Gamma-oryzanol interacts with any medicines. Before taking Gamma-oryzanol, talk with your healthcare professional if you take any medications.
There are no known interactions with herbs and supplements.
There are no known interactions with foods.
Gamma-oryzanol has most often been used by adults in doses of 100-300 mg by mouth daily. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Gama Orizanol, Gamma Oryzanol, Gamma-OZ, Oryzanol.
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