Polypodium leucotomos is a tropical fern from Central and South America. It's been used in traditional medicines.
Polypodium leucotomos contains chemicals that might have antioxidant effects. The antioxidants in Polypodium leucotomos might prevent damage caused by excessive sun exposure.
People use Polypodium leucotomos for sunburn, eczema, dark skin patches on the face, cancer, and many other conditions, but there is no good scientific evidence to support these uses.
Is It Effective?
There is interest in using Polypodium leucotomos for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Is it Safe?
When taken by mouth: Polypodium leucotomos extract is possibly safe when used in doses of 360-480 mg daily for up to 6 months. It seems to be well-tolerated.
When applied to the skin: Polypodium leucotomos extract is possibly safe when used short-term.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if Polypodium leucotomos is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Children: Polypodium leucotomos extract is possibly safe when taken by mouth at varying doses by age for up to 6 months.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)
Interaction Rating=Minor Be watchful with this combination.
Some medications are changed and broken down by the liver. Polypodium leucotomos might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
There are no known interactions with herbs and supplements.
There are no known interactions with foods.
Polypodium leucotomos has most often been used by adults in doses of 360-960 mg by mouth daily for 2-26 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Anapsos, Calaguala, Difur, Fern, Fougère, P. Leucotomos, PL, PLE, Polypodium.
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