Health & Well-Being A-Z

Secretin

Doctor holds in one hand laboratory test tube with blood, in other figure of pancreas
Description

Secretin is a hormone produced by the digestive tract. It is used as a medicine. Some secretin products are taken from pigs, while others are made in the laboratory. Two dosage forms are available as drugs. Secretin is either placed under the tongue or given by IV (intravenously).

Secretin is used to treat autism, schizophrenia, and many other conditions, but there is no good scientific evidence to support these uses.

Is It Effective?

Effectiveness header

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

Likely ineffective
  • Autism. Although some parents have reported an improvement in stomach and intestinal function, social and behavioral abilities, and language skills after single intravenous doses of secretin, high-quality clinical research shows that secretin does not work any better than placebo for improving symptoms of autism.
Insufficient evidence
  • Swelling (inflammation) of the pancreas (pancreatitis). Some early research shows that secretin might help improve symptoms of chronic pancreatitis. But not all research agrees.
  • Schizophrenia. Early research shows that secretin does not help people with schizophrenia.
  • Intestinal ulcers.
  • Digestive tract bleeding.
  • Heart failure.
  • Other conditions.

More evidence is needed to rate the effectiveness of secretin for these uses.

Is it Safe?

Action

Secretin is a hormone that is produced by the digestive tract. It stimulates the release of bicarbonate and water from the pancreas to aid digestion.

Safety

When given by IV: Secretin is LIKELY SAFE when the prescription product is given by IV by a healthcare provider. Common side effects of secretin include flushing of the face, neck, and chest immediately after a dose. Less common side effects are vomiting, diarrhea, fainting, blood clot, fever, and rapid heartbeat. Some people can have allergic reactions including hives, redness of the skin, and a life-threatening allergic reaction (anaphylaxis).

When given under the tongue: There isn't enough reliable information to know if secretin is safe or what the side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if secretin is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Drug interactions

It is not known if Secretin interacts with any medicines. Before taking Secretin, talk with your healthcare professional if you take any medications.

Herb interactions

There are no known interactions with herbs and supplements.

Food interactions

There are no known interactions with foods.

Dosage

The appropriate dose of secretin depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for secretin. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Other names

Oxykrinin, Secretina, Sécrétine.

Disclaimer

Information on this website is for informational use only and is not intended to replace professional medical advice, diagnosis, or treatment. While evidence-based, it is not guaranteed to be error-free and is not intended to meet any particular user’s needs or requirements or to cover all possible uses, safety concerns, interactions, outcomes, or adverse effects. Always check with your doctor or other medical professional before making healthcare decisions (including taking any medication) and do not delay or disregard seeking medical advice or treatment based on any information displayed on this website.

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