The Hormone Intelligence Framework for Sustainable Well-Being: Empowering Patients Toward A Healthier Tomorrow

In this illuminating conversation, internationally recognized dietitian and integrative nutrition leader Ashley Koff, RD introduces her Hormone Intelligence Framework—a practical, science-backed path to restoring the body’s natural weight-health rhythms.

Drawing from 25+ years as a practitioner, educator, and founder of The Better Nutrition Program, Ashley breaks down how everyday choices can naturally activate the body’s weight-health hormones—GLP1, GIP, CCK, and PYY—the same pathways targeted by drugs like semaglutide, tirzepatide, Ozempic®, and Wegovy®. She helps us understand what the popularity of these medications reveals about widespread dysfunction in satiety and weight-regulating hormones, and why “better, not perfect” nutrition offers a more sustainable way forward.

This episode invites listeners to build a relationship with their own hormone intelligence, using nutrition, lifestyle rhythm, and gut-brain balance to cultivate sustainable vitality and regenerative well-being.

In this episode, you will learn:

• Weight-Health hormone Optimization: Tools to naturally activate your body’s weight-health hormones, GLP1, GIP, CCK, PYY—the same ones replaced by semaglutide, tirzepatide, Ozempic®, Wegovy®.

• What GLP1s Are Really Telling Us: What the popularity of these drugs reveals about widespread dysfunction in satiety and weight-regulating hormones.

• How to develop strategies to tune out food noise and fight “INFObesity.”

• Nutrition as Hormone Therapy: How fiber, phytonutrients, protein timing, and microbiome diversity naturally stimulate weight health hormones.

• Beyond Weight Loss: How stabilizing blood sugar and repairing gut health improve energy, cognition, and long-term disease prevention.

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